Mass Spec Imaging Services



Protea’s Research Laboratory brings you access to the most advanced and cutting-edge mass spectrometry imaging (MSI) technologies and workflows.
Available MSI Methods:
  • LAESI-MSI
  • MALDI-MSI
  • Combined analytical services

Supported Applications:
  • Drug target interaction and localization
  • Metabolomics investigations
  • Biomarker geographical distribution surveys
  • Chemical histopathology studies
  • In vivo mass spectrometry investigation


Our Research Laboratory is your critical partner for mass spec-based molecular distribution profiling. Using proprietary technologies (such as LAESI-MSI) and more traditional methodologies (like MALDI-MSI), we provide you with distribution profiling in two and three dimensions of tissues, biofilms, and even living populations (such as cell cultures, bacteria, and fungal colonies). We can also combine imaging data acquired by different analytical techniques to build a deeper, more comprehensive investigation.

By combining cutting-edge products and instrumentation with the experience and expertise of our team, we provide your organization with the comprehensive and holistic support you deserve. Our team works with you, providing either standardized MSI protocols, or customized methods specific to your application.

Case Studies and App Notes:

Cross Platform Lipid Imaging of Silver Nanoparticle-Exposed Rat Brain by LAESI-MS and MALDI-MS

In situ Detection and Imaging of Ergot Alkaloids in Ipomea tricolor by LAESI-MS-MS and MALDI-MS

In situ Top Down Proteomics: Targeted Imaging of Proteins in Tissue Using Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI-MS)
…imaging the future of biology