Posters and Publications:

Posters and Publications:

Download Center

New Case Study

Metabolite Profiling of Glyphosate Exposed Saccharomyces cerevisiae with REDIchips™

REDIchips are silicon nanopost array (NAPA) devices which allow for the detection and profiling of metabolites in different strains of glyphosate exposed Saccharomyces cerevisiae. Laser Desorption Ionization Mass Spectrometry (LDI-MS) using REDIchips eliminates the requirement of an external matrix, and minimizes noise in low mass regions of the spectra where metabolites are detected.

view this publication

Rapid Screening and Quantitation of Domoic Acid in Shellfish Homogenates Using Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI-MS)

A Combined Enzymatic Digestion and Matrix Application Approach for High Throughput MSI of FFPE Tissue

Laser Ablation Electrospray Ionization Mass Spectrometry Imaging (LAESI-MSI) using an Er:YAG Laser for Improved Spot Size Resolution and Tunable Ablation

Detection Enhancement of Small Molecules, Lipids and Peptides by Functionalizing Silicon Nanopost Arrays With Fluorous Monolayers

Peptide Screening Using Nanopost Array Laser Desorption Ionization Mass Spectrometry (NAPA LDI-MS) on Fluorinated REDIchips™

N-Glycan Profiling and Amino Acid and Monosaccharide Composition of Antibodies by LCMS

Monoclonal Antibody Disulfide Bond Shuffling Assessment by Multiple Enzyme Digest

Mass Spectrometry Imaging Determines Biomarkers of Early Adaptive Precision Drug Resistance in Lung Cancer

Molecular Imaging of Biological Samples on Nanophotonic Laser Desorption Ionization Platforms

High Throughput Screening of Urine Marker Codes by Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI MS)

Pain Panel Drug Screening by Nanopost Array Laser Desorption Ionization Mass Spectrometry (NAPA LDI-MS) on REDIchip™

Method development of LC-MS based peptide quantitation assay to differentiate kininogen and kallikrein cleaved kininogen

Stability Analysis of the Human IgG1 Antibody

Cross Platform Lipid Imaging of Silver Nanoparticle-Exposed Rat Brain by LAESI-MS and MALDI-MS

Quantitative Mass Spectrometry Imaging of Rabbit Skin Topically Dosed with an Antifungal Compound using a Stable Isotope Labeled Internal Standard

In situ Detection and Imaging of Ergot Alkaloids in Ipomea tricolor by LAESI-MS-MS and MALDI-MS

REDIchips for Rapid Quantitation of Low Molecular Weight Pharmaceutical Drugs Using Laser Desorption Ionization Mass Spectrometry

REDIchips for Applied Quantitation of Alkaloids

ntegration of MS Imaging and Proteomic Data for Biological Discovery in a 3D Microtissue Model of Colon Cancer

In situ Top Down Proteomics: Targeted Imaging of Proteins in Tissue Using Laser Ablation Electrospray Ionization Mass Spectrometry (LAESI-MS)

Metabolomic Profiling of Biofluids Using Laser Desorption Ionization on Nanopost Array Devices (REDIchips)

A Novel Web Interface to Facilitate Histology Guided Mass Spectrometry

Proteomic Analysis in the Lung and Brain of Rats Following Silver Nanoparticle Inhalation

Histology Guided Mass Spectrometry Determines Proteomic Differences Associated with Carbon Nanotube Exposure in the Lung

Nanostructured Laser Desorption Ionization Device for Small Molecule Analysis

Analysis of mixed biofilm (Staphylococcus aureus and Pseudomonas aeruginosa) by laser ablation electrospray ionization mass spectrometry

Observation of Subcellular Metabolite Gradients in Single Cells by Laser Ablation Electrospray Ionization Mass Spectrometry

High-throughput quantitative analysis of domoic acid directly from mussel tissue using Laser Ablation Electrospray Ionization – tandem mass spectrometry

Combining Laser Ablation Electrospray Ionization Mass Spectrometry with Collision Cross Section for Improved Metabolite and Lipid Identification from Clinical Samples

Mass Spec Imaging Differentiates Histological Subtypes of Stage 1 Pulmonary Adenocarcinoma

Development of a LC-MS-MS method for Quantitation of Decoquinate and Levamisole in Equine Plasma

Direct Analysis of Animal and Plant Tissues by LAESI-MSI with Ion Mobility for Mapping of Metabolites and Lipids

Digging Deeper – Using Acid Labile Detergents to Uncover More of the Mass Spectrometry Imaging Proteome

High Throughput Spatially Resolved Peptide Identification using Hydrogel Digestion and Electro-Elution

Increased Sensitivity in LAESI-MS Analyses using a Heated Extension Tube for the Direct Analysis of Plants

Rapid Profiling of Arbuscular Mycorrhizal Fungi Spores Using LAESI-MS

Single Bead Peptide Microarrays Characterized by LAESI-MS

MSI of Skin Wound Healing Biomarkers Using LAESI-MS

Toward single-cell analysis by plume collimation in laser ablation electrospray ionization mass spectrometry

Relative quantitation in single-cell metabolomics by laser ablation electrospray mass spectrometry

Simultaneous detection of nonpolar and polar compounds by heat-assisted laser ablation electrospray ionization mass spectrometry

Comparative local analysis of metabolites, lipids and proteins in intact fish tissues by LAESI mass spectrometry

A General Approach to Anionic Acid-Labile Surfactants with Tunable Properties

Direct Sample Analysis Without Extraction Using LAESI-MS

2D and 3D Direct Analysis of Plant Tissues

Mass Spectrometry Imaging of Raclopride and Fexofenadine in Whole Body Mouse Tissue Using LAESI-MS

A Lipidomic Imaging Analysis of Mouse Brain Using LAESI-MS in Positive and Negative Ion Modes Coupled with Ion Mobility Spectrometry

LAESI Mass Spectrometry Imaging of Contact Lens Spoilage

Online Core-Shell HPLC Protein Separation and Top-Down Proteomics Using High Resolution Mass Spectrometry

Protein Profiling of Animal Tissues Using LAESI-MS

GPR-800 Poster

Three-Dimensional Imaging of Metabolites in Tissues under Ambient Conditions by Laser Ablation Electrospray Ionization Mass Spectrometry

Metastable Atom-Activated Dissociation Mass Spectrometry of Phosphorylated and Sulfonated Peptides in Negative Ion Mode

Characterization of Tyrosine Nitration and Cysteine Nitrosylation Modifications by Metastable Atom-Activation Dissociation Mass Spectrometry

Metastable Atom-Activated Dissociation Mass Spectrometry: Leucine-Isoleucine Differentiation and Ring Cleavage of Proline Residues

Direct Analysis of Lipids and Small Metabolites in Mouse Brain Tissue by AP IR-MALDI and Reactive LAESI-MS

Molecular Mass Spectrometry Imaging in Biomedical and Life Science Research

Ambient mass spectrometry for in vivo local analysis and in situ molecular tissue imaging

Rapid, non-targeted discovery of biochemical transformation and biomarker candidates in oncovirus-infected cell lines using LAESI mass spectrometry

Direct Analysis of Phycobilisomal Antenna Proteins and Metabolites in Small Cyanobacterial Populations by Laser Ablation Electrospray Ionization Mass Spectrometry

Internal energy deposition and ion fragmentation in atmospheric-pressure mid-infrared laser ablation electrospray ionization

Top-Down Proteomics Using High Resolution Mass Spectrometry and Online Core-Shell HPLC Protein Separation

2D and 3D Imaging of Biological Samples Using a Novel Integrated LAESI-MS Source

Overview: Laser Ablation Electrospray Ionization (LAESI)

Metabolic Profiling of Biofluids by LAESI-MS

Direct 2D and 3D Metabolic Profiling of Flower Petals Using LAESI-MS

Profiling metabolites and peptides in single cells

In Situ Cell-by-Cell Imaging and Analysis of Small Cell Populations by Mass Spectrometry

Direct Detection of Diverse Metabolic Changes in Virally Transformed and Tax-Expressing Cells by Mass Spectrometry

Direct Analysis of Single Cells by Mass Spectrometry at Atmospheric Pressure

Atmospheric-pressure Molecular Imaging of Biological Tissues and Biofilms by LAESI Mass Spectrometry

Direct analysis of lipids and small metabolites in mouse brain tissue by AP IR-MALDI and reactive LAESI mass spectrometry

Minimally invasive monitoring of cellulose degradation by desorption electrospray ionization and laser ablation electrospray ionization mass spectrometry

Molecular mass spectrometry imaging in biomedical and life science research

Simultaneous Imaging of Small Metabolites and Lipids in Rat Brain Tissues at Atmospheric Pressure by Laser Ablation Electrospray Ionization Mass Spectrometry

Laser Ablation Electrospray Ionization for Atmospheric Pressure Molecular Imaging Mass Spectrometry

Ablation and analysis of small cell populations and single cells by consecutive laser pulses

In Situ Metabolic Profiling of Single Cells by Laser Ablation Electrospray Ionization Mass Spectrometry

Three-Dimensional Imaging of Metabolites in Tissues under Ambient Conditions by Laser Ablation Electrospray Ionization Mass Spectrometry

In vitro analysis of metabolites from the untreated tissue of Torpedo californica electric organ by mid-infrared laser ablation electrospray ionization mass spectrometry

Ambient Molecular Imaging and Depth Profiling of Live Tissue by Infrared Laser Ablation Electrospray Ionization Mass Spectrometry

Molecular imaging by Mid-IR laser ablation mass spectrometry

Laser Ablation Electrospray Ionization for Atmospheric Pressure, in Vivo, and Imaging Mass Spectrometry