Bioanalytical Services >> Large Molecule: Quantitation by LC-MS/MS

Whether investigating a biomarker or the pharmacokinetics and toxicokinetics of a biologic compound, Protea is dedicated to developing innovative technologies to improve the quality of data obtained from your valuable biological samples. Your samples will be analyzed using advanced instrumentation, including high resolution exact mass MS/MS technology as well as the most advanced triple quadrupole systems and software. Protea combines over 20 years of experience working with large molecules to offer mass spectrometry-based large molecule quantification services to provide confidence in your sample data and complete technical support for your project.

Services are available for:
  • Novel assay development
  • Assay transfer
  • Quantitative analysis using advanced chromatography techniques
  • GLP or Fit-for-Purpose (FFP) assay validation and sample analysis

Our mass spectrometry-based quantitative assays have many benefits required for verification studies, including: high specificity, sensitivity, multiplexing capability and precision, while providing a method for direct detection of protein targets.

Examples of Large Molecule Bioanalytical Services:

  • Biomarker quantitation
  • Bioavailability studies
  • Signature peptide and MRM assays
  • Immunoprecipition and immunoaffinity capture assays
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