LAESI^® DP-1000 >> LAESI-Based Services

Direct Ionization Mass Spectrometry Analysis Using Protea LAESI DP-1000 System
Protea can now provide direct identification and characterization of biological samples through its proprietary LAESI DP-1000 System interfaced with ion trap technology or ion mobility TOF.

All LAESI-MS Bianalytical Services are reported through a secure, interactive online portal, where you will receive email notifications upon sample receipt, processing stage, and final data report creation.

Services are available for:

• Profiling biological tissues
• Profiling living cells/colonies
• TLC plate separation profiling
• Direct analysis of biological fluids
• Real time redox reaction monitoring
• Material characterization

LAESI, or Laser Ablation Electrospray Ionization is a technique used to profile the spatial distribution of metabolites, lipids, peptides, proteins, and other biomolecules in a wide variety of sample types under ambient conditions with minimal sample handling. Detailed reports include publication quality images and standard MS datasets.

Examples of LAESI-MS Bioanalytical Services
2D and 3D Tissue Imaging

• Biomolecular spatial distribution mapping
• Molecular identification, characterization, and relative quantitation
• Drug detection and localization in forensic samples
• 2D MS contour plot generation
• 3D tissue depth profiling without sample slicing

High-Throughput Biofluid Analysis

• 96 and 384 well plate analysis
• Temperature controlled environment for bioreaction monitoring
• Molecular identification, characterization and relative quantitation

Biodynamic cell colony monitoring

• In situ colony metabolite profiles
• Drug to cell interaction