Advanced Proteomics

Protea’s Reseach Laboratory offers mass spectrometry based proteomics services to answer your most intriguing bioanalytical questions.

Using your input, our experienced proteomics scientists will design a strategy that efficiently analyzes your samples of interest and provides you with data you need. Our state-of-the-art instrumentation and expertise gives you access to the more traditional and the most advanced proteomics services. We utilize an integrated approach to services focused on upstream sample preparation, downstream mass spectrometric analysis, and project consultation.

We offer several proteomics modalities for your project’s specific needs. We offer services in the following areas:
Qualitative MS Proteomics
  • Specialized PTM analysis
  • N-Linked oligosaccharide mapping
  • Global proteome characterization
  • Peptide mapping
  • Assessment of the disulfide bridge patterns
  • Intact protein analysis
  • ETD

Quantitative MS proteomics:
  • MRM assay
  • iTRAQ
  • Label Free Quantitation

Gel Based Services:
  • 1D and 2D SDS PAGE
  • Intact protein gel recovery and MS analysis

Case Studies and App Notes:

CASE STUDY: Direct Characterization of Cysteine Binding in Signal Transduction Pathways by LC MS-MS

Label-Free Quantitation of Proteins in Human Prostate Cancer Patient Plasma

CASE STUDY: Biomarker Discovery in Human Prostate Cancer Patient Samples Using Combined MuDPIT and BIOiTRAQ Workflows
…concepts into knowledge